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In both acute and chronic sinusitis, inflammation and edema leads to obstruction of sinus ostia that further exacerbates the disease

The unbalance in pro- and anitioxidants may have increased susceptibility of brain PUFAs to oxidative damage and subsequently contributed to the deterioration of brain structure and cognitive impairment during the course of the disease [23, 24, 76, 8294]

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Reported benefits included: Average systolic blood pressure reductions of 45 mm Hg in men Drops of 23 mm Hg in women Reductions of up to 11 mm Hg in overweight participants Some reductions were comparable to the effects of blood pressure medication

Patients with suspected B12 deficiency should consult their GP for proper diagnosis and investigation of underlying causes before starting treatment