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For weight management purposes, B12 injections are not clinically indicated unless deficiency is documented

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In the Discussion we consider whether the oxidation of cysteine residues might still be obscured by other routes of countervailing sulfenate/disulfide reduction

For example, ceruloplasmin is a copper-containing ferroxidase that possesses ferroxidase and antioxidant activity and inhibits iron-and copper-dependent lipid peroxidation and scavenging peroxide and superoxide anions

Animal studies show comparable efficacy from 10 ng/kg to 10 mg/kg, spanning a 1000-fold range