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Introduction The field of regenerative medicine has experienced considerable advancement with the development of peptide-based therapeutics targeting tissue repair and homeostatic maintenance

Hepatic stellate cells as key target in liver fibrosis

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Meningococcus primarily utilizes hemoglobin, transferrin, and lactoferrin as a source of iron, via specific outer membrane systems such as HmbR/HupAB for hemoglobin/heme and TbpA/TbpB and LbpA/LbpB for transferrin and lactoferrin, respectively

Cellular uptake is facilitated by the H-coupled oligopeptide transporter PepT1, through which KPV accumulates intracellularly and suppresses downstream pro-inflammatory cytokine expression, including TNF-, IL-6, and IL-8 (Dalmasso et al