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However, the expression of other surface receptors, including TLR2, 4, 5 and 9, enables GI macrophages to carry out antigenic clearance from the lamina propria via phagocytic uptake, while also maintaining an anti-inflammatory gut environment (Smith et al

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Vasculogenesis is also described in adults during capillary formation post ischemia [41] or in tumors as alternative mechanism for neo-vascularization to meet the increasing need for oxygen and nutrient supply [42]

Commercial payers follow similar frameworks but may impose additional utilisation management requirements including prior authorization, step therapy protocols, or quantity limits