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Front Immunol 5:221228

10.1016/j.compbiomed.2021.104754 72 SamuelB

The accumulation of proteins in the ER membrane, namely ER overload, leads to release of calcium ions from the ER and production of reactive oxygen species

FoxOs are involved in the control of angiogenesis, stem cell proliferation, cell adhesion, oxidative stress responses, as well as innate and acquired immunity