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Thus, by multiplying an ACO's average per capita savings or losses across BY1 and BY2 by a financial risk scaling factor equal to 2/3 , we would impose a downward reduction on the prepaid shared savings multiplier by assuming that it would have been possible, in principle, for an ACO to have not earned any per capita savings in the performance year that constitutes BY3 of the current agreement period

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References Quercia, S

Additionally, CDs can be functionalized with targeting ligands such as antibodies or peptides to further improve specificity for cancer cells