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Furthermore, translocations and fusions of NIK (NF-B-inducing kinase) and NF-B1, two genes and gene-product proteins occur with the involvement of apoptosis inhibitor IAP (another hallmark of malignant transformation) (16,17)

When taken orally, proteins, vitamins and minerals in food must be digested to be absorbed by the body

In brain injury, the microglia response switches from a proinflammatory M1 to an anti-inflammatory/reparative M2 for recovery

Glutathione, often dubbed the "master antioxidant," is a crucial molecule produced naturally within our cells

Furthermore, under OA-related inflammatory and metabolic stress environments, cells may promote GPX4 ubiquitination and subsequent proteasomal degradation by inducing specific E3 ubiquitin ligase activity, thereby increasing cellular susceptibility to ferroptosis (Su et al., 2025