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Identification of UNC10415667, a benzaldehyde containing NSD2 degrader While UNC10088 and UNC8732 are promising cell-free and cell-based tool compounds, respectively, we were interested in developing non-prodrug analogs that could similarly engage FBXO22 to promote NSD2 degradation without requiring bioactivation for activity

This product has not been evaluated or approved by Health Canada, the U.S

Health risks associated with overweight and obesity

Available from: Yoshimura S, Suemizu H, Nomoto Y, Sakai H, Katsuoka Y, Kawamura N et al

Oral, Intravesical, Local, and Injection-Based Research Contexts The registered Phase 1 PCO-02 study used an oral tablet context, the interstitial cystitis pilot used intravesical administration during cystoscopy, and the knee pain report used an intra-articular route [12] [13] [14]