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Some African populations have a higher prevalence of slow acetylators, individuals who metabolize 5-ASA derivatives more slowly, potentially leading to reduced drug effectiveness and an increased risk of adverse effects

These clusters are a key part of the cellular defense mechanism against TE mobilization and include damaged TE fragments [431, 437, 438]

In the core loop of Drosophila , transcription factors dCLOCK (dCLK) and CYCLE (CYC) form a heterodimer to activate the expression of core-clock genes, such as period ( per ) and timeless ( tim ), in addition to other clock and clock-controlled downstream genes

Psychiatry 89 , 970979 (2021)

Liang S, Gong F, Zhao X (2009) Prokaryotic expression, puri- fication of a new tumor-relative protein FAM92A1-289 and its characterization in renal cell carcinoma