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[PubMed] [Google Scholar] 52.Allan CM, Taylor S, Taylor JM

Biol Psychiatry 78:702710 Mandal PK, Goel A, Bush AI, Punjabi K, Joon S, Mishra R, Tripathi M, Garg A, Kumar NK, Sharma P, Shukla D, Ayton SJ, Fazlollahi A, Maroon JC, Dwivedi D, Samkaria A, Sandal K, Megha K, Shandilya S (2022) Hippocampal glutathione depletion with enhanced iron level in patients with mild cognitive impairment and Alzheimers disease compared with healthy elderly participants

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Moreover, animal models data strongly agree that overexpression of -syn leads to a direct insult to the dopaminergic system, reported as a decrease in tyrosine hydroxylase (TH) activity and expression within the striatum [36]