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An in vitro study of human bronchial epithelial cells from patients with COPD or asthma showed that increased oxidant burden may lead to reduced corticosteroid responsiveness in airway epithelium, with important consequences for the integrity of the epithelial barrier and associated production of pro-inflammatory cytokines [43]

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[PubMed: 25591052] 2

High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth