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PMID: 37375654

Protein synthesis inhibition and oxidative stress induced by cylindrospermopsin elicit apoptosis in primary rat hepatocytes

Asian J Pharmaceutics (AJP)

In cancer cells, elevated ROS levels not only promote proliferation and invasion but also contribute to the malignancy of tumors by modulating the tumor microenvironment, enhancing angiogenesis, and facilitating extracellular matrix remodeling

The activation of AMPK promotes the clearance of misfolded proteins such as -synuclein and supports the function of mitochondria by stimulating peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1, a regulator of biogenesis of mitochondria)