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Identification of sulfenylated cysteines in Arabidopsis thaliana proteins using a disulfide-linked peptide reporter

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[42] [43] These properties contribute to the depletion of cysteine from respiratory chain complexes, such as Complexes I and IV, [44] since reactive oxygen species (ROS) produced by the respiratory chain can react with the cysteine residues in these complexes, leading to dysfunctional proteins and potentially contributing to aging

The honest answer is that glutathione work is mostly quiet: it supports cellular steadiness rather than producing a dramatic, immediate change