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CSF analysis for oligoclonal bands was not available, but given the normal MRI findings, it was unlikely to change the diagnosis

Storage in a cool, dry, and light-protected environment is recommended to maintain material integrity

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Notably, the lipid profile of HSL-inhibited M2 macrophages shifted away from the M2 cluster and toward the M1 cluster, providing direct evidence that HSL activity is essential for maintaining the M2-specific lipidome (Supplementary Fig

First-line treatments usually consist of hormonal treatmentsuch as a hormonal IUD (coil) or continuous use of a birth control pillcombined with a non-steroidal anti-inflammatory drug (NSAID) like naproxen