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This VEGF stimulation promotes angiogenesis and blood vessel formation critical for tissue oxygenation and nutrient delivery, accelerating healing across all tissue types

Many people notice improvements within a few weeks of treatment, although full recovery can take several months depending on the severity of the deficiency

A Canadian study published in JAMA found that people with diabetic kidney disease experienced faster decline in kidney function when given high doses of B12 and B6 compared to those who received a placebo

The maximum total dose currently recommended to be given in the ED is 16 mg, however, studies are ongoing exploring giving higher total doses up to 32 mg9

This is compared to a 2.4% loss of weight in those taking a placebo