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Glutathione inside cells jumps into action, binding to these toxins and transforming them into less harmful compounds that can be safely eliminated (Ballatori et al., 2009)

Abnormal blood vessel formation also leads to a decrease in the infiltration of effector immune cells, which mediate immune escape and can reduce the efficacy of immunotherapy by impeding drug delivery

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doi:10.3390/toxins8110326 Lombardo M, Aulisa G, Marcon D, et al