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The fixed-effect meta-analysis assumes that there is insignificant variation between the estimates of the same parameter across different replicates

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Cell Rep 2(3):470477 Brehove M, Wang T, North J, Luo Y, Dreher SJ, Shimko JC, Ottesen JJ, Luger K, Poirier MG (2015) Histone core phosphorylation regulates DNA accessibility

Surprisingly, the current study has shown that plasma Hcy was not elevated but instead decreased in the first 2 weeks following pemetrexed therapy (Figure 4)