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It has been shown that the increase in insulin resistance was halted after nicotine replacement was stopped, and even improved during continuous weight gain, [78] implying that nicotine rather than weight gain may be responsible for the initial increase in insulin resistance observed in some smoking-related studies

The Spanish preferred the "smooth" taste of Nicotinia tabacum compared to Nicotinia rustica , but began growing both species on Caribbean and South American plantations in the 1500's

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So, I figured since it was a small plant, it would be indoor friendly