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Dietary phytochemicals alleviate the premature skin aging: a comprehensive review

In vivo-directed evolution was used to optimize the activity of TYO in the biosynthetic pathway and the hydroxytyrosol whole-cell biosensor was used for high-throughput screening

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doi: 10.1002/jsfa.12263 136

They are widely used in anti-aging formulations because they support collagen synthesis, skin regeneration, and barrier repair when efficiently delivered to target skin layers