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Superoxide dismutase (SOD) is a metalloenzyme that catalyses the dismutation of the superoxide anion radical to molecular oxygen and hydrogen peroxide, thereby reducing the intracellular concentration of free metal cations and attenuating the damage caused by H 2 O 2 (Feng and Wang 2020)

doi:10.1016/S0753-3322(03)00043-X

Such a combination ensures efficient and targeted delivery of genetic material to the brain by overcoming BBB

Yet, even in an era of unprecedented scientific collaboration, many of the studies reviewed here exhibit substantial variability in experimental design and treatment approacheshindering meaningful comparisons and challenging the reproducibility of results