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The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress

10.3390/ijms22179286 175 MunshiN.JeayS.LiY.ChenC

This, in turn, would drive oxidatively induced cell death and increase barrier dysfunction and T2 inflammation, potentially identifying a mechanism by which viruses cause asthma exacerbations