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Discussion In this nationwide population-based cohort with comprehensive data on health status and medical service utilization of the entire Korean population, smoking reduction and smoking cessation were independently associated with a lower risk of lung cancer development in patients with COPD who smoked less than 30 pack-years, after adjusting for major confounders, including cumulative smoking amount and sociodemographic factors

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1-3 Months : The inhale/exhale function is greatly improved

Individual metabolite classes have also been quantified in flue-cured tobacco leaves in previous research [3, 27,28,29]