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Thus, in this small trial of children with non-syndromic ASD and language impairment, treatment with high-dose folinic acid for 12 weeks resulted in improvement in verbal communication as compared with placebo, particularly in those participants who were positive for FRAAs

This beneficial effect was (among other mechanisms) linked to ROS metabolism

The study demonstrated that nanoencapsulated polyphenols significantly enhanced antioxidant levels, hepatic function, and food consumption compared to nonencapsulated treatments (135)

( H ) Histogram showing the acrophase distribution of renal proteins assigned to dryR rhythmicity models 2, 3, 4, and 5

Available from: Serbin GM, de Barros Pinang DS, Machado RM, Vasconcelos S, Amorim BS, Clement CR