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Furthermore, daridorexant, a dual orexin receptor antagonist, has shown promise in extending total sleep duration and reducing daytime sleepiness in cirrhosis patients, though caution is advised for those with advanced cirrhosis (Child C class) (31)

In particular, the non-specific ROS scavenger, phenyl N-tert-butylnitrone (PBN), administered according to an intervention protocol in rats administered paclitaxel, attenuated development of mechanical (Kim et al., 2010) and cold hypersensitivity in the hindpaws (Fidanboylu et al., 2011)

Each daily dose (2 x 600mg capsules) is the equivalent of approximately 12g of fresh broccoli sprouts - about a cup - and delivers a guaranteed minimum of 6mg of sulforaphane.8

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