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While initially adaptive, prolonged or severe ER stress leads to excessive ROS production, further exacerbating cellular injury (Zhang et al., 2025)

In the quest to restore cellular bioenergetics, nutritional interventions have taken center stage in complex chronic illness care

This Review aims to help researchers make informed decisions when choosing an experimental design that best aligns with the specific requirements of their projects, whilst meaningfully replicating human disease

This process, through the use of sulfur-containing compound such as glutathione, taurine, and SAMe, helps to detoxify sulfur-containing chemicals found in food additives, drugs, and the environment, all of which can be potentially harmful to the body

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