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Arabi and Shareghi, Interestingly, seminal fluid NIC concentrations are high in men passively exposed to cigarette smoke (10.7 8.5 ng/ml) (Pacifici et al., We have shown that NIC damages, in a concentration-dependent manner, both conventional and non-conventional sperm parameters (Condorelli et al., in vitro effects of NIC on sperm motility and non-conventional sperm parameters: mitochondrial function, viability and chromatin/DNA integrity (Condorelli et al., in vitro (Condorelli et al., NIC binds to a class of ionotropic acetylcholine receptors, the nicotinic receptors (nAChRs), made up of five subunits

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