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How you organize the building blocks really tells you what kind of effect you are going to have. Synthetic or lab-made peptides can mimic those the body makes naturally, but with tweaks to make the compound more druglike, says Eileen Kennedy, president-elect of the nonprofit American Peptide Society

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However, HIF-1 is considered as a potential regulator of intestinal permeability during regular exercise-induced hypoxia (Yu et al., 2022)