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SKU: 97345043623
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Third, not all POIs are equally amenable to CRBN- or VHL-based degraders, possibly due to incompatibilities in surface topologies and hence an inability to form a productive ternary complex 21,22,23

10.3389/fcimb.2022.924119 Front

In contrast, the corresponding residue of L142 in the D14 group was the highly conserved V143 ShD14 (Supplementary Figs

Bnger, M., de Groot, P

Tong Y, Wu Y, Ma J, Ikeda M, Ide T, Griffin CT, Ding XQ, Wang S (2023) Comparative mechanistic study of RPE cell death induced by different oxidative stresses