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IgG4-sclerosing cholangitis causes a clinical picture very similar to PSC, which is characterised by elevated IgG4 levels and there may be other features of IgG4-related disease (e.g

doi: 10.1042/bj2100289

In comparison to the control group, the cohort treated with Rhodiola exhibited restored 5-HT concentrations, an increased prevalence of BrdU-positive and double-labeled cells, as well as normalized neuron quantities

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This approach could reveal new opportunities for using multitarget inhibitors effectively