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Also, a fraction of the iodinated compounds in the serum of patients with Hashimoto's thyroiditis is not soluble in butanol, as are the thyroid hormones, but is an abnormal peptide-linked iodinated component

14 The FDA suggests that if a patient does not improve after 24 continuous weeks of Zoloft treatment, the dose be titrated upwards to see if the patient will see improvement at a higher dose

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