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Notably, nicotine itself is not directly linked to the severe health issues associated with smoking

Although lengthy lists of potential confounding factors have been offered as alternatives to direct associations of secondhand smoke exposures with the risk for disease, the factors on these lists generally have not been shown to be confounding in the particular data of interest

Frequent and heavy cannabis use can lead to addiction, specifically Cannabis Use Disorder, which research shows affects 3 in 10 users

Zhao D, Aravindakshan A, Hilpert M, Olmedo P, Rule AM, Navas-Acien A, Aherrera A

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