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So when were saying biotin causes acne because it affects B5 levels, how much biotin do you need to be consuming for it to affect B5

There are other 5-Amino-1MQ benefits due to its NNMT inhibition, including: Slowing down aging High NNMT levels reduce NAD+ and increase homocysteine (Hcy)

The most common causes include B12 supplementation (particularly injections), liver disease releasing stored B12, haematological disorders increasing B12-binding proteins, and chronic kidney disease reducing B12 excretion

I typically use a B complex to support multiple areas of health, unless theres a clear need for high doses of one nutrient

10, 11a and b)