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Adolescent THC exposure causes enduring prefrontal cortical disruption of GABAergic inhibition and dysregulation of sub-cortical dopamine function

Increased NO activity influences synaptic signaling in ways that can dampen neurotransmitter turnover relevant because both dopamine and serotonin are tied to the hedonic tone (baseline sense of reward and emotional engagement) that anhedonia disrupts

Zudem wird Citrus Aurantium hufig in Produkten zur Untersttzung der Gewichtsreduktion und Steigerung der Energie eingesetzt

Sommer et al., Reference Sommer, Kropat, Malasarn, Grossoehme, Chen, Giedroc and Merchant2010)

Pain 30 (1), 4450