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Of the adverse experiences judged to be of "possible" relationship to the study drug, anxiety, incoordination, and nervousness were reported following intramuscular vitamin B12 and headache, nausea, and rhinitis were reported following dosing with Nascobal (Cyanocobalamin, USP) Gel for Intranasal Administration

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ALDH1A1 and ODC1, in particular, contribute to a tumour-promoting microenvironment, with high expression levels linked to poor prognosis 62,63

No non-compartmental analysis was conducted for drug plasma concentrations measured after SL BUP administration on Day 1

Opa1, similar to Drp1, binds CL, and this interaction drives membrane fusion