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Description

Cellular quality control by the ubiquitin-proteasome system and autophagy

Peptide GLP-1 agonists activate both Gs-cAMP and beta-arrestin pathways, with relative bias varying among different agonists

When intake explains the result and the patient is well, with no concerning clinical or laboratory findings,it can often be attributed as the likely cause without an extensive search for disease

The primary efficacy measures were the patients survival rate (time to death or full ventilation support) and their changes in functional ability (measured by ALSFRS-R scores)