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To mitigate this, future studies should consider incorporating objective biomarkers of nicotine exposure, such as cotinine levels in blood or urine, to provide a more accurate assessment of tobacco use and minimize the risk of reporting bias

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[9] While current e-cigarette use declined among middle and high school youth from 2015 to 2016, [ 10 ] between 2017 and 2018, current e-cigarette use grew by 78% among high school students and by 48% among middle schools students, driven largely by new USB-shaped e-cigarette product Juul