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aKG is an intermediate metabolite substrate of the tricarboxylic acid cycle (TAC, which is essential for cellular metabolism [144]

Additionally, GPX4 knockdown significantly suppresses tumor cell proliferation in vitro and in vivo

After sample protein injection, 2 column volumes (CV) of 10 mM sodium phosphate buffer, pH 7.4, were used to elute unbound material, followed by 10 CV of a gradient to 50% buffer containing 2 M NaCl ( i.e