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Notably, the G/D-CuP group showed the lowest ratio of CD86-positive macrophages/CD206-positive macrophages, indicating an enhanced M1-to-M2 transition (Supplementary Fig

The shunts are through ophthalmic vein, angularis vein, facial anterior and posterior vein, and facial vein, or through cerebri superior veins, sinus cavernosus, sinus petrosus superior and inferior, sinus transversus, through jugular external vein, subclavia vein through superior caval vein

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Eventually, a plateau occurs

For this, concentrations of 10 4 , 10 6 and 10 8 cfu/ml of bacteria were prepared according to McFarland standards, and then quantification and confirmation tests of culturable bacteria were performed