Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) Size:100mg Product Name DCAF1 Binder 13

Product Name DCAF1 Binder 13 Synonyms CAS Number n/a Related CAS Molecular Formula C28H35ClN6O Molecular Weight 507

589 Purity (HPLC) >= 95% Solubility DMSO

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

85 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(=O)NCCCN=[N]#N)C3=CC=CC=C3C2(C)C)N(CCCS([O-])(=O)=O)C2=CC=CC=C12 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

7-dihydroxy-4-phenylcoumarin CAS Number 7758-73-8 Related CAS Molecular Formula C15H10O4 Molecular Weight 254

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) Size:100mg Product Name DCAF1 Binder 13SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from