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In the process, proteases remove the C-terminal globular domain

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In non-clinical research literature, the GHK-Cu peptide is discussed as a signaling molecule that works at the cellular level, including effects on human genes tied to tissue repair, collagen synthesis, collagen and elastin remodeling, glycosaminoglycan expression, and overall skin quality within controlled laboratory systems

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Cells were treated with various concentrations of GSSSG (25200 M) or LPS (10 g/mL) for 6 h, and then living cells were detected using Calcein-AM