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Kalkan et al

Biological target: Restoration of youthful pulsatile GH release, which declines by approximately 14% per decade after age 30

The last finding is primary to understanding that reduced metabolic processes could induce potential side effects of fentanyl, mainly when highly prevalent non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD) co-exist (Alkhouri et al., 2022), but not only