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Alzheimers disease shares gene expression aberrations with purinergic dysregulation of HPRT deficiency (Lesch-Nyhan disease)

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Finally, when the tumor is located near the ventricular lining or has a large cystic cavity, the infusate will distribute into these lower pressure gradient areas and leave the areas of more viable tumor, which typically have higher interstitial pressures, uncovered by infusate [81]