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Metabolic drivers of non-alcoholic fatty liver disease

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The loss of function of the Stella protein leads to an arrest in embryo development associated with a loss of 5mC both in male and female pronuclei (Nakamura et al., 2007)

The structure was solved by molecular replacement with the unphosporylated GSK3 structure (Dajani et al ., 2001) (PDB code 1H8F) using AMoRe (Navaza, 1994), which resolved the space group as P 6 1 22, and was refined using CNS (Brnger et al ., 1998)