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Hyperglycemia can lead to excessive production of ROS, which is not only a major factor in aging, but also one of the leading causes of diabetes complications, insulin resistance, and mitochondrial dysfunction (63)

Glucose transport: pivotal step in insulin action

Because the condition results directly from retained toxins rather than primary inflammation, standard therapies like nonsteroidal anti-inflammatory drugs or colchicine are ineffective, making hemodialysis the only definitive, life-saving intervention

A PEDOT: PSS-based composite hydrogel as a versatile electrode for wearable microneedle sensing platforms

Copolymerization of pNcollagen III and collagen I