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Unlike the smooth surface of LNPs containing cholesterol, LNPs containing -sitosterol had a multifaceted surface, which might be caused by the changes in the surface lipid composition 723 and could enhance the fusion of LNPs with membranes, 724 thus leading to higher mRNA delivery efficiency

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Microspheres Microspheres are particulate dispersion systems formed when a drug is dispersed or adsorbed in a polymer or polymeric matrix