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Description

Blockade of GCH1/BH4 axis activates ferritinophagy to mitigate the resistance of colorectal cancer to erastin-induced ferroptosis

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Uricosuric agents like dotinurad enhance UA excretion by targeting specific enzymes involved in purine metabolism

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Winther KH, Wichman JE, Bonnema SJ, Hegeds L (2017) Insufficient documentation for clinical efficacy of selenium supplementation in chronic autoimmune thyroiditis, based on a systematic review and meta-analysis

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In the trioLR analyses, we relied on permutation testing to gage whether signals occurred by chance, and again encourage both replication and biological plausibility as additional milestones for validation

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It remains to be investigated whether other pathogenic bacteria utilize GSH for virulence through its conversion to H 2 S

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