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Graphical abstract Similar content being viewed by others The importance of autophagy in cell homeostasis Autophagy and the ubiquitin proteasome system (UPS) are two major intracellular degradative mechanisms that mediate the catabolism of proteins and organelles

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Experiment 1 Discrete effects of MR were determined by feeding six groups of eight- week-old male F344 rats (n = 8/group) for 12 weeks

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