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To isolate the metabolic changes directly associated with oxidative burst from those generally induced by stimulation, we compared the metabolomic profiles of neutrophils stimulated with zymosan, TNF-, PsA or PMA for 30 min, with or without treatment with the NOX inhibitor DPI (Fig

Methionine is less hydrophobic than valine and therefore substitution to methionine should have lessened the aggregation propensity

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Baseline demographic data, BMI, etiology of cirrhosis, MELD-Na pre-hospitalization and on hospital presentation were collected