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In contrast, previous studies have reported the use of plasma collected exclusively in sodium heparin tubes 67,68 , which is acceptable for determining oxalate in most clinical laboratories

Such results imply that metformin could aggravate tau pathology, potentially via the overactivation of AMPK and downstream GSK3, since excessive AMPK activity has been linked to tau aggregation in other models [181]

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Redman, C

In non-human research, it has shown relevance in the regulation of gene expression tied to regeneration, collagen production, and oxidative stress recovery