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J Neuropathol Exp Neurol (2002) 61:101321.10.1093/jnen/61.11.1013 57 JackCSArbourNManusowJMontgrainVBlainMMcCreaEet alTLR signaling tailors innate immune responses in human microglia and astrocytes

The c-Jun NH 2 -terminal kinase (JNK) pathway is activated by OS and cytokines (tumor necrosis factor- and FAS) and, similar to the ERK pathway, stimulates a cascade of phosphorylation reactions involving MAPKKK, MAPKK, and ultimately phosphorylating JNK on threonine and tyrosine residues

Furthermore, while there is substantial evidence supporting the significance of autophagy in various conditions such as cancer, neurodegenerative diseases, and infectious diseases, it's important to note that, as of now, no specific autophagy inhibitor or inducer has gained regulatory approval for use in cancer or any other disease [121]

A decrease in the poly-metabolic risk scores of MASLD FMT recipients by week 24, was used to determine their response status to FMT